Imagen

Prioritize drug targets from a ranked gene list (e.g., scRNA-seq DE output) by orchestrating parallel API queries against UniProt, OpenTargets (with integrated DepMap CRISPR essentiality + gnomAD constraint), PubMed, the Human Protein Atlas (HPA), and ChEMBL tool compounds, then re-ranking by a composite score combining protein localization, druggability, disease genetics, tissue specificity (safety), focus-cell-type expression, CRISPR essentiality, LoF safety constraint, and research maturity. Use whenever the user wants to filter, triage, prioritize, or "do due diligence" on a list of candidate genes for drug discovery, especially after a DE / DEG analysis when they say things like "which of these should I follow up on", "filter for druggable targets", "make a target dossier", "rank these for tractability", "annotate these genes for druggability", or "build a target report". Trigger even when the user says just "filter these candidate genes" or hands over a CSV from a DE pipeline.

React 18/19 patterns including hooks discipline, server/client component boundaries, Suspense + error boundaries, form actions, data fetching, state management decision trees, and accessibility-first composition. Use when writing or reviewing React components.

Query onchain data on Base using the CDP SQL API via x402. Use when you or your user want to view onchain information about decoded blocks, transactions, and events.

Vite build tool patterns including config, plugins, HMR, env variables, proxy setup, SSR, library mode, dependency pre-bundling, and build optimization. Activate when working with vite.config.ts, Vite plugins, or Vite-based projects.

Generate and edit images using OpenAI's Image API for project assets — UI mockups, icons, illustrations, social cards, and visual references.

Guide for feature flags and A/B tests with the Flags SDK (`flags` npm package) and Vercel Flags. Use when: declaring flags with `flag()`, using `vercelAdapter` or `vercel flags` CLI (add, list, enable, disable, inspect, archive, rm, sdk-keys), setting up providers/adapters (Vercel, Statsig, LaunchDarkly, PostHog, GrowthBook, Hypertune, Global Config, OpenFeature, Split, Flagsmith, Reflag, Optimizely, or custom adapters), implementing precompute patterns for static pages, setting up `identify`/`dedupe`, integrating Flags Explorer/Toolbar, working with flags in Next.js (App Router, Pages Router, Middleware) or SvelteKit, writing custom adapters, or encrypting/decrypting flag values. Triggers: feature flags, A/B testing, experimentation, flags SDK, flag adapters, precompute, Flags Explorer, feature gates, flag overrides, Vercel Flags, vercel flags CLI, vercel flags add, vercel flags list, vercel flags enable, vercel flags disable, `flags/next`, `flags/sveltekit`, `flags/react`, `@flags-sd