Tooluniverse Drug Repurposing

This is a structured workflow for finding new uses for existing drugs. It walks you through three strategies: target-based (disease gene to drug lookup), compound-based (drug to new indication), and disease-driven (disease to target to drug). The workflow is opinionated about reasoning first before running searches, includes a scoring rubric that weighs genetic evidence and safety profiles, and comes with specific tool call patterns for OpenTargets, DrugBank, DGIdb, and clinical trial databases. Most useful when you're hypothesis-generating for rare diseases or need to systematically evaluate repurposing candidates with a consistent evidence framework. The documentation is thorough about parameter names and response paths, which matters since these APIs aren't always intuitive.

Install to Claude Code

npx -y skills add mims-harvard/tooluniverse --skill tooluniverse-drug-repurposing --agent claude-code