Ensembl Database

If you're doing genomic research and need to pull data from Ensembl, this connects you to their REST API for 250+ species. You can look up genes by symbol or ID, grab DNA/protein sequences, run variant effect predictions through VEP, find orthologs across species, and convert coordinates between genome assemblies like GRCh37 to GRCh38. The skill includes both the ensembl_rest Python package and direct API examples with proper rate limiting (15 requests per second). Most useful when you're building analysis pipelines that need gene annotations, comparative genomics data, or variant analysis and want to avoid manually wrangling the API.