Neurokit2

If you're working with physiological data, this is the toolkit you need. It handles ECG, EEG, EDA, EMG, respiratory signals, and more through a unified API. The real power is in the comprehensive analysis pipelines: you get complete HRV metrics across time/frequency/nonlinear domains, EEG microstate segmentation, EDA decomposition into tonic and phasic components, and a full complexity analysis suite with entropy and fractal measures. It's built for psychophysiology research but works just as well for clinical applications or human-computer interaction studies. The event-related analysis features make it easy to epoch data around stimuli. One thing to know: it integrates with MNE for advanced EEG work, so you're not locked into a single ecosystem.