Daily Paper Generator

Spatial multi-omics interpretation pipeline. Transforms spatially variable genes (SVGs), domain annotations, and tissue context into biological insights via domain-by-domain characterization, cell-type composition, spatial gene expression patterns, RNA+protein+metabolite integration. Use for Visium, MERFISH, seqFISH, Slide-seq, spatial proteomics, and spatial multi-omics interpretation. Goes beyond statistics to disease mechanisms and therapeutic opportunities.

Use this skill when the user wants to debug, diagnose, or systematically iterate on an experiment that already exists, or when they need a structured experiment log for tracking runs, hypotheses, failures, results, and next steps during active research. Apply it to underperforming methods, training that will not converge, regressions after a change, inconsistent results across datasets, aimless experimentation without progress, and questions like 'why doesn't this work?', 'no progress after many attempts', or 'how should I investigate this failure?'. Also use it for setting up practical experiment logging/record-keeping that supports debugging and iteration. Do not use it for designing a brand-new experiment pipeline or full experiment program (use experiment-pipeline), generating research ideas, fixing isolated coding/syntax errors, or writing retrospective summaries into research memory/notes/knowledge bases.

Expert SEO content strategy for SaaS and B2B sites. Use when doing keyword research, planning content clusters, creating pillar pages, optimizing on-page SEO, fixing technical SEO issues, building links, refreshing content, implementing programmatic SEO, mapping search intent, optimizing for SERP features, or measuring content performance. Use for SEO audits, content gap analysis, and organic growth strategy.

Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.

Compare GWAS studies, perform meta-analyses across cohorts, and assess signal replication. Uses GWAS Catalog metadata, study-level statistics, and cross-cohort comparison. Use for evaluating GWAS reproducibility for a trait, meta-analysis sample size and effect-size aggregation, and detecting study heterogeneity (population, design, ancestry).

Detect and auto-install missing ToolUniverse research skills. Checks common Claude Code/Cursor/Codex skill directories for the canary file, and installs any missing skills if none found. Use when the plugin's research skills aren't loading, when migrating between clients, or when verifying a skill installation.