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k-dense-ai avatar

Polars Bio

k-dense-ai/scientific-agent-skills
1.1k installs33k stars
Summary

A Polars-native library for genomic interval operations that's 6-38x faster than bioframe on real-world benchmarks. Handles the usual interval arithmetic (overlap, nearest, merge, coverage, complement, subtract) plus reads and writes BED, VCF, BAM, CRAM, GFF, FASTA, and FASTQ files. Built on Apache Arrow and DataFusion, so you get streaming support for datasets that don't fit in memory and native cloud I/O for S3, GCS, and Azure. Ships with both functional and method-chaining APIs, plus a SQL interface if that's your thing. Worth trying if you're doing genomic analysis in Python and already use Polars, or if you're hitting performance walls with existing tools.

Install to Claude Code

npx -y skills add k-dense-ai/scientific-agent-skills --skill polars-bio --agent claude-code

Installs into .claude/skills of the current project.

CodeRabbit
CodeRabbit
AI writes the code. CodeRabbit catches the slop.
Try For Free →
Lid closed, agents working
Lid closed, agents working
Keeps your Mac awake while Claude Code, Codex or Cursor works. Lets it sleep when they are done.
Try free for 7 days →
Block distraction from your iPhone for freeBlock distraction from your iPhone for free
Block distraction from your iPhone for free
Block distracting apps from your iPhone permanently without a 3rd party app. Free and open source.
Block now (100% free) →
Granola, the best AI meeting recorder
Granola, the best AI meeting recorder
Notes, actions and memory. Without a meeting bot. First month 100% off.
Download for free →
belt - the only tool your agent needs
belt - the only tool your agent needs
belt cli automatically finds the best tools and skills for your agent. image, video, music, tts...
one prompt install →
Open Steps
Open Steps
Free an open-source skills that make AI coding agents easier to understand, verify, and control.
Download for free →
AppSignal
AppSignal
Monitor with ease. Code with confidence.
Start Free Trial →
Agent, connect blockchain
Agent, connect blockchain
Connect your Claude agent to live crypto prices and trading routes via 1inch
Get the MCP →
CodeRabbit
CodeRabbit
AI writes the code. CodeRabbit catches the slop.
Try For Free →
Lid closed, agents working
Lid closed, agents working
Keeps your Mac awake while Claude Code, Codex or Cursor works. Lets it sleep when they are done.
Try free for 7 days →
Block distraction from your iPhone for freeBlock distraction from your iPhone for free
Block distraction from your iPhone for free
Block distracting apps from your iPhone permanently without a 3rd party app. Free and open source.
Block now (100% free) →
Granola, the best AI meeting recorder
Granola, the best AI meeting recorder
Notes, actions and memory. Without a meeting bot. First month 100% off.
Download for free →
belt - the only tool your agent needs
belt - the only tool your agent needs
belt cli automatically finds the best tools and skills for your agent. image, video, music, tts...
one prompt install →
Open Steps
Open Steps
Free an open-source skills that make AI coding agents easier to understand, verify, and control.
Download for free →
AppSignal
AppSignal
Monitor with ease. Code with confidence.
Start Free Trial →
Agent, connect blockchain
Agent, connect blockchain
Connect your Claude agent to live crypto prices and trading routes via 1inch
Get the MCP →
Files
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Featured
CodeRabbit
CodeRabbit
AI writes the code. CodeRabbit catches the slop.
Try For Free →
Lid closed, agents working
Lid closed, agents working
Keeps your Mac awake while Claude Code, Codex or Cursor works. Lets it sleep when they are done.
Try free for 7 days →
Block distraction from your iPhone for freeBlock distraction from your iPhone for free
Block distraction from your iPhone for free
Block distracting apps from your iPhone permanently without a 3rd party app. Free and open source.
Block now (100% free) →
Granola, the best AI meeting recorder
Granola, the best AI meeting recorder
Notes, actions and memory. Without a meeting bot. First month 100% off.
Download for free →
belt - the only tool your agent needs
belt - the only tool your agent needs
belt cli automatically finds the best tools and skills for your agent. image, video, music, tts...
one prompt install →
Open Steps
Open Steps
Free an open-source skills that make AI coding agents easier to understand, verify, and control.
Download for free →
AppSignal
AppSignal
Monitor with ease. Code with confidence.
Start Free Trial →
Agent, connect blockchain
Agent, connect blockchain
Connect your Claude agent to live crypto prices and trading routes via 1inch
Get the MCP →
Categories
Testing & QAGit & Pull RequestsAI & Agent BuildingData Science & MLDebuggingCloud & Infrastructure
First SeenJun 3, 2026
View on GitHub

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Use when investigating Jetpack Compose recomposition performance, skippable/restartable composables, composables.txt or compiler reports, Layout Inspector recomposition counts, back-writing snapshot state across phases, or frame-rate State reads in composition vs layout/draw, and it is not yet clear whether the cause is parameter stability, deferred reads, or cross-phase back-writing.
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