Reactome Database

If you're doing pathway enrichment or systems biology work, this gives you direct access to Reactome's 2,825+ curated human pathways through their REST API. You can run overrepresentation analysis on gene lists, analyze expression data, map proteins to pathways, and explore disease mechanisms. The API returns JSON with p-values and pathway mappings, plus tokens that stay valid for seven days so you can retrieve results later. It includes both the Content Service for querying pathway data and the Analysis Service for statistical enrichment. The reactome2py Python wrapper is available but hasn't been updated since 2021, so you might want to hit the REST endpoints directly for anything complex.

Install to Claude Code

npx -y skills add davila7/claude-code-templates --skill reactome-database --agent claude-code