Uniprot Database

Direct REST API access to UniProt for protein lookups, FASTA retrieval, and ID mapping across databases like Ensembl, RefSeq, and PDB. You get search by gene name or accession, batch operations for up to 100k IDs, and streaming for large datasets. The included Python client handles the common patterns. One thing to know: if you're already working in Python with multiple bioinformatics databases, bioservices gives you a unified interface to 40+ services including UniProt. This is better when you need UniProt-specific control or you're doing direct HTTP work outside a Python workflow.