Tooluniverse Disease Research

This generates comprehensive disease research reports by querying 10 different databases and assembling everything into a structured markdown file. It hits OpenTargets for genetics and drugs, pulls phenotypes from HPO, checks ClinVar for variants, queries clinical trials, and maps pathways through Reactome. The workflow is report-first: it creates the file upfront and progressively fills sections as it researches, with mandatory source citations for every data point. What stands out is the evidence grading system and the explicit instruction to look up facts rather than rely on training data, which matters for medical information that changes. Produces tables with genes, variants, drugs, trials, and pathways. Best for rare diseases or when you need a full intelligence brief on a condition.

Install to Claude Code

npx -y skills add mims-harvard/tooluniverse --skill tooluniverse-disease-research --agent claude-code