Tooluniverse Drug Drug Interaction

This analyzes drug interactions with a report-first workflow that checks local pharmacology references before hitting external databases. It covers both CYP450 and UGT enzyme interactions (the valproate-lamotrigine SJS risk gets explicit treatment), bidirectional perpetrator-victim analysis, and evidence grading for clinical claims. The local script handles common high-risk pairs like statins with azoles, warfarin with inducers, and prodrug activation failures. Use it when reviewing polypharmacy cases or when a patient develops new symptoms after starting a medication. The framework pushes you to reason mechanistically about inhibition versus induction before consulting references, which makes the output more clinically useful than a simple interaction flag.

Install to Claude Code

npx -y skills add mims-harvard/tooluniverse --skill tooluniverse-drug-drug-interaction --agent claude-code