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Built for the Claude Code community with Claude Code by @mertduzgun

Independent project, not affiliated with Anthropic
  1. MCP
  2. /
  3. ChatSpatial

ChatSpatial

Editor's Note

Wraps 65 spatial transcriptomics methods into 20 schema-validated MCP tools so LLMs can orchestrate reproducible workflows instead of generating arbitrary analysis scripts. Covers the standard pipeline: load 10x Visium or Xenium data, identify spatial domains with SpaGCN or STAGATE, deconvolve with Cell2location or RCTD, run cell-cell communication via LIANA, annotate with Tangram or scANVI, and compute spatial statistics like Moran's I or Ripley's K. Tool parameters constrain method selection, turning natural language prompts into deterministic calls. Particularly dense for multi-sample integration (Harmony, scVI), trajectory inference (CellRank, Palantir), and spatially variable gene detection (SpatialDE, SPARK-X). Designed for researchers who want conversational access to ScanPy-adjacent tooling without writing Python notebooks.

Install

claude mcp add --transport stdio cafferychen777-chatspatial uvx chatspatial
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