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Independent project, not affiliated with Anthropic
pipeworx-io avatar

Ncbi Eutils

pipeworx-io/mcp-ncbi-eutils
HTTPregistry active
Summary

Wraps the NCBI E-utilities API so Claude can search and retrieve records from PubMed, Gene, Nucleotide, and the rest of the Entrez database ecosystem. You get six core operations: einfo for database metadata, esearch for running queries and getting UIDs, esummary for quick record overviews, efetch for full records in XML/GenBank/FASTA formats, elink for cross-database relationships, and egquery for searching across all databases at once. Hosted via Pipeworx's gateway with streamable HTTP transport, so no local setup. Useful when you need Claude to pull literature references, gene sequences, or protein data directly from NCBI without manual API wrangling.

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@pipeworx/ncbi-eutils

NCBI E-utilities MCP — federated search and fetch across all NCBI Entrez databases: PubMed, Gene, Nucleotide, Protein, Taxonomy, ClinVar, dbSNP, OMIM, BioProject, BioSample, SRA, … Keyless (3 req/s without key).

Part of Pipeworx — an MCP gateway connecting AI agents to 1476+ live data sources.

Tools

  • einfo(db?) — database info / field list
  • esearch(db, term, retmax?, retstart?, sort?) — search → uid list
  • esummary(db, ids, retstart?) — summary records by uid
  • efetch(db, ids, rettype?, retmode?) — full records
  • elink(dbfrom, dbto, ids, linkname?) — links across databases
  • egquery(term) — global query across all databases

Data source

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "ncbi-eutils": {
      "url": "https://gateway.pipeworx.io/ncbi-eutils/mcp"
    }
  }
}

What this endpoint actually serves

tools/list at https://gateway.pipeworx.io/ncbi-eutils/mcp returns the tools in the table above plus the shared Pipeworx meta-tools — ask_pipeworx, discover_tools, search_within, remember/recall and the rest of the gateway-wide set. So the tool count you see is larger than this table: a single-pack endpoint currently lists roughly 30 shared tools alongside the pack's own. The connection's initialize response states its exact scope, and is the authoritative answer for a given day.

This is deliberate, not multiplexing by accident. The meta-tools are what let a scoped connection answer a question this pack does not cover — via ask_pipeworx, which routes across the whole catalog — without you adding a second MCP server. There is currently no way to mount a pack endpoint without them; if the extra schemas cost you more context than the routing is worth, connect to the full gateway once rather than to several pack endpoints.

Or connect to the full Pipeworx gateway to get every pack's tools listed directly, instead of just this one's:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Both URLs reach the same gateway and the same 1476+ data sources. The only difference is which pack's tools are listed directly; ask_pipeworx reaches all of them from either one.

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English — this works on the pack endpoint above as well as on the full gateway:

ask_pipeworx({ question: "your question about Ncbi Eutils data" })

The gateway picks the right tool and fills the arguments automatically.

More

  • Docs and guides
  • pipeworx.io

License

MIT

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Categories
Search & Web Crawling
Registryactive
TransportHTTP
UpdatedMay 16, 2026
View on GitHub

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