Summary
Connects to the Saccharomyces Genome Database, the go-to resource for baker's yeast genetics and molecular biology. Part of the Pipeworx gateway, which means you can either use this SGD-specific endpoint or tap into their full collection of 815+ data sources through a single gateway. The repo doesn't list specific tools, but you can query it through their ask_pipeworx interface using plain English questions about yeast genomics data. Useful if you're working on comparative genomics, researching gene function in a model organism, or need programmatic access to curated yeast data without scraping SGD's web interface yourself.
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mcp-sgd
SGD (Saccharomyces Genome Database) MCP.
Part of Pipeworx — an MCP gateway connecting AI agents to 1476+ live data sources.
Tools
| Tool | Description |
|---|---|
get_gene | Look up a single yeast (S. cerevisiae) gene/locus in SGD (Saccharomyces Genome Database, the authoritative budding-yeast genetics resource). Accepts a systematic name (e.g. YAL001C), a standard gene name (e.g. TFC3), or an SGDID (e.g. S000000001). Returns the standard name, systematic name, SGDID, description, locus type, and aliases. Keyless. |
search_genes | Search SGD (Saccharomyces Genome Database, the authoritative budding-yeast / S. cerevisiae genetics resource) for genes, loci, alleles, and other entities by free-text query. Returns matching hits with their name, category, and href. Keyless. |
get_gene_go | Get Gene Ontology (GO) annotations for a yeast (S. cerevisiae) gene/locus from SGD (Saccharomyces Genome Database). Accepts a systematic name (e.g. YAL001C), a standard gene name (e.g. TFC3), or an SGDID (e.g. S000000001). Returns GO terms with their GO id, aspect (molecular function / biological process / cellular component), and supporting evidence. Keyless. |
Quick Start
Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):
{
"mcpServers": {
"sgd": {
"url": "https://gateway.pipeworx.io/sgd/mcp"
}
}
}
What this endpoint actually serves
tools/list at https://gateway.pipeworx.io/sgd/mcp returns the tools in the table
above plus the shared Pipeworx meta-tools — ask_pipeworx,
discover_tools, search_within, remember/recall and the rest of the
gateway-wide set. So the tool count you see is larger than this table: a
single-pack endpoint currently lists roughly 30 shared tools alongside the
pack's own. The connection's initialize response states its exact scope, and
is the authoritative answer for a given day.
This is deliberate, not multiplexing by accident. The meta-tools are what let a
scoped connection answer a question this pack does not cover — via
ask_pipeworx, which routes across the whole catalog — without you adding a
second MCP server. There is currently no way to mount a pack endpoint without
them; if the extra schemas cost you more context than the routing is worth,
connect to the full gateway once rather than to several pack endpoints.
Or connect to the full Pipeworx gateway to get every pack's tools listed directly, instead of just this one's:
{
"mcpServers": {
"pipeworx": {
"url": "https://gateway.pipeworx.io/mcp"
}
}
}
Both URLs reach the same gateway and the same 1476+ data sources. The
only difference is which pack's tools are listed directly; ask_pipeworx
reaches all of them from either one.
Using with ask_pipeworx
Instead of calling tools directly, you can ask questions in plain English — this works on the pack endpoint above as well as on the full gateway:
ask_pipeworx({ question: "your question about Sgd data" })
The gateway picks the right tool and fills the arguments automatically.
More
License
MIT
No MCP client? Call it over HTTP
curl -X POST https://gateway.pipeworx.io/v1/tools/sgd_get_gene \
-H 'Content-Type: application/json' \
-d '{"id":"YAL001C"}'
No account needed for the first calls. Inspect any tool: GET https://gateway.pipeworx.io/v1/tools/sgd_get_gene. Find one: POST https://gateway.pipeworx.io/v1/tools/search_packs with {"query":"..."}.
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