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pipeworx-io avatar

Sgd

pipeworx-io/mcp-sgd

Connects to the Saccharomyces Genome Database, the go-to resource for baker's yeast genetics and molecular biology. Part of the Pipeworx gateway, which means you can either use this SGD-specific endpoint or tap into their full collection of 815+ data sources through a single gateway. The repo doesn't list specific tools, but you can query it through their ask_pipeworx interface using plain English questions about yeast genomics data. Useful if you're working on comparative genomics, researching gene function in a model organism, or need programmatic access to curated yeast data without scraping SGD's web interface yourself.

last updated
Jun 9, 2026
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Readme

mcp-sgd

SGD (Saccharomyces Genome Database) MCP.

Part of Pipeworx — an MCP gateway connecting AI agents to 1857+ live data sources. This is an independent, unofficial integration — not affiliated with, endorsed by, or published by the upstream provider.

Tools

ToolDescription
get_geneLook up a single yeast (S. cerevisiae) gene/locus in SGD (Saccharomyces Genome Database, the authoritative budding-yeast genetics resource). Accepts a systematic name (e.g. YAL001C), a standard gene name (e.g. TFC3), or an SGDID (e.g. S000000001). Returns the standard name, systematic name, SGDID, description, locus type, and aliases. Keyless.
search_genesSearch SGD (Saccharomyces Genome Database, the authoritative budding-yeast / S. cerevisiae genetics resource) for genes, loci, alleles, and other entities by free-text query. Returns matching hits with their name, category, and href. Keyless.
get_gene_goGet Gene Ontology (GO) annotations for a yeast (S. cerevisiae) gene/locus from SGD (Saccharomyces Genome Database). Accepts a systematic name (e.g. YAL001C), a standard gene name (e.g. TFC3), or an SGDID (e.g. S000000001). Returns GO terms with their GO id, aspect (molecular function / biological process / cellular component), and supporting evidence. Keyless.

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "sgd": {
      "url": "https://gateway.pipeworx.io/sgd/mcp"
    }
  }
}

What this endpoint actually serves

tools/list at https://gateway.pipeworx.io/sgd/mcp returns the tools in the table above plus the shared Pipeworx meta-tools — ask_pipeworx, discover_tools, search_within, remember/recall and the rest of the gateway-wide set. So the tool count you see is larger than this table: a single-pack endpoint currently lists roughly 30 shared tools alongside the pack's own. The connection's initialize response states its exact scope, and is the authoritative answer for a given day.

This is deliberate, not multiplexing by accident. The meta-tools are what let a scoped connection answer a question this pack does not cover — via ask_pipeworx, which routes across the whole catalog — without you adding a second MCP server. There is currently no way to mount a pack endpoint without them; if the extra schemas cost you more context than the routing is worth, connect to the full gateway once rather than to several pack endpoints.

Or connect to the full Pipeworx gateway to get every pack's tools listed directly, instead of just this one's:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Both URLs reach the same gateway and the same 1857+ data sources. The only difference is which pack's tools are listed directly; ask_pipeworx reaches all of them from either one.

No MCP client? Call it over HTTP

curl -X POST https://gateway.pipeworx.io/v1/tools/sgd_get_gene \
  -H 'Content-Type: application/json' \
  -d '{"id":"YAL001C"}'

No account needed for the first calls. Inspect any tool: GET https://gateway.pipeworx.io/v1/tools/sgd_get_gene. Find one: POST https://gateway.pipeworx.io/v1/tools/search_packs with {"query":"..."}.

Run it from npm

@pipeworx/mcp-sgd is a local stdio bridge to the Pipeworx gateway: your MCP client starts it with npx, and it forwards every call to the same https://gateway.pipeworx.io/sgd/mcp endpoint shown above. It needs network access; there is no offline mode.

{
  "mcpServers": {
    "sgd": {
      "command": "npx",
      "args": ["-y", "@pipeworx/mcp-sgd"]
    }
  }
}

Without a key it calls anonymously, capped at 50 calls a day. A free account raises that to 200 a day: get a key at https://pipeworx.io/signup and add "env": { "PIPEWORX_API_KEY": "<your key>" } to the server entry. The key is sent as a Bearer token, the same way a hosted connection sends it, so calls are metered and billed exactly as they are there.

It lists only this pack's tools by default. Set PIPEWORX_META_TOOLS=1 to also list ask_pipeworx and the other gateway-wide tools.

Behind an HTTPS proxy: Node's built-in fetch does not read HTTPS_PROXY by default. Newer Node releases honour it when NODE_USE_ENV_PROXY=1 is set; check your Node version's documentation.

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English — this works on the pack endpoint above as well as on the full gateway:

ask_pipeworx({ question: "your question about Sgd data" })

The gateway picks the right tool and fills the arguments automatically.

More

  • Docs and guides
  • pipeworx.io

License

MIT

Details

Repository
github.com/pipeworx-io/mcp-sgd
Website
pipeworx.io/packs/sgd
Category
Databases
Transport
HTTP
Registry
MCP registry, active

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