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Independent project, not affiliated with Anthropic
pkotecha-eng avatar

Aria Mcp Server

pkotecha-eng/aria-mcp-server
1STDIOregistry active
Summary

This connects Claude to three public biomedical APIs: PubMed's 35M+ papers via NCBI E-utilities, ClinicalTrials.gov's 400K+ trials, and the ISRCTN UK/European registry. You get three search tools, three structured prompts for common workflows like adverse event analysis and trial eligibility checking, and reference resources covering trial phases and FDA databases. No API keys needed since all three endpoints are public. Built with FastMCP. Reach for this when you're doing literature reviews, screening patients against recruiting trials, or cross-referencing published evidence with active drug studies. The prompts handle the boilerplate for generating clinical research briefs and safety profiles.

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🧬 ARIA Clinical Research MCP Server

A standalone MCP server that gives any Claude agent real-time access to biomedical literature and clinical trials — no API keys required. aria-mcp-server MCP server

Tools

ToolDescription
search_pubmedSearch 35M+ peer-reviewed papers via NCBI E-utilities
search_clinical_trialsSearch 400K+ trials via ClinicalTrials.gov v2 API
search_isrctnSearch UK/European trials via ISRCTN registry

Prompts

PromptDescription
clinical-research-briefComprehensive evidence + trial brief for a condition
adverse-event-analysisStructured AE and safety profile for a drug
trial-eligibility-checkerPatient eligibility assessment across recruiting trials

Resources

ResourceDescription
info://ariaOverview of ARIA capabilities and data sources
reference://trial-phasesPhase I–IV definitions and FDA special designations
reference://high-impact-journalsCurated high-impact journals by specialty
reference://fda-databasesFDA databases for drug, safety, and regulatory research

Example queries

Once connected, ask Claude:

  • "Search PubMed for ketogenic diet pediatric epilepsy outcomes"
  • "Find recruiting trials for lung cancer immunotherapy"
  • "What does the literature say about veliparib in ovarian cancer, and are there active trials?"
  • "Find UK and European trials for pediatric epilepsy via ISRCTN"

Quickstart

pip install aria-mcp-server
aria-mcp-server

Connect to Claude Desktop

Add to ~/Library/Application Support/Claude/claude_desktop_config.json:

{
  "mcpServers": {
    "aria-clinical-research": {
      "command": "aria-mcp-server"
    }
  }
}

Restart Claude Desktop. The server will appear under Settings → Developer → Local MCP Servers.

Data sources

  • PubMed — NCBI E-utilities (public API, no key required)
  • ClinicalTrials.gov — v2 REST API (public API, no key required)
  • ISRCTN — UK/European clinical trials registry (public API, no key required)

Tech stack

  • FastMCP — MCP server framework
  • Python 3.12+

Use cases

  • Life sciences researchers needing real-time literature access
  • Clinical trial coordinators checking eligibility and recruiting status
  • Drug discovery teams cross-referencing published evidence with active trials
  • Any Claude agent needing grounded biomedical knowledge

Project Structure

aria-mcp-server/          ← root, where mcp-publisher runs
├── aria_mcp_server/      ← Python package
│   ├── __init__.py
│   ├── server.py
│   └── tools.py
├── server.json           ← MCP registry metadata
├── pyproject.toml
├── README.md
├── LICENSE
└── glama.json

Built by

Pooja Kotecha · dinq.me/pkotecha-eng

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Categories
Search & Web Crawling
Registryactive
Packagearia-mcp-server
TransportSTDIO
UpdatedMay 4, 2026
View on GitHub

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