Gnomad

This server wraps the Broad Institute's gnomAD database, exposing five GraphQL backed tools for querying genomic variant data. You get variant lookups by coordinates or rsID, gene queries with variant lists, region scans up to 25kb, transcript details, and autocomplete search. It runs through Pipeworx's gateway infrastructure, which means you can either connect directly to gnomAD or use their unified endpoint for 250+ data sources. The ask_pipeworx tool lets you skip manual tool selection and just ask questions in plain English. Useful if you're building genomics workflows in Claude and need quick access to population frequency data, pathogenicity predictions, or variant annotations without standing up your own gnomAD queries.