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Gtex

pipeworx-io/mcp-gtex
HTTPregistry active
Summary

Connects Claude to the GTEx (Genotype-Tissue Expression) project's human gene expression data via Pipeworx's gateway. You get five tools: look up gene metadata by Gencode ID or symbol, pull median expression levels across tissues in TPM, find top expressed genes for a specific tissue, query significant single-tissue eQTLs, and list available tissues. Useful when you're doing genomics research or building tools that need to cross-reference gene symbols with expression patterns in specific human tissues. Part of Pipeworx's broader gateway covering 250+ data sources, but available as a standalone endpoint if you only need GTEx.

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mcp-gtex

GTEx MCP.

Part of Pipeworx — an MCP gateway connecting AI agents to 673+ live data sources.

Tools

ToolDescription
geneGene metadata by Gencode id or symbol.
median_expressionMedian expression across tissues for a gene (TPM).
top_expressed_genesTop expressed genes for a tissue.
single_tissue_eqtlsSignificant single-tissue eQTLs for a gene.
tissuesList of tissues.

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "gtex": {
      "url": "https://gateway.pipeworx.io/gtex/mcp"
    }
  }
}

Or connect to the full Pipeworx gateway for access to all 673+ data sources:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English:

ask_pipeworx({ question: "your question about Gtex data" })

The gateway picks the right tool and fills the arguments automatically.

More

  • All tools and guides
  • pipeworx.io

License

MIT

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Registryactive
TransportHTTP
UpdatedMay 18, 2026
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