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Ebi Ols

pipeworx-io/mcp-ebi-ols
HTTPregistry active
Summary

Connects Claude to the EBI Ontology Lookup Service, giving you programmatic access to over 250 biomedical ontologies including EFO, MONDO, and Gene Ontology. You get six tools: list and search ontologies, retrieve term details by IRI or OBO ID, and traverse hierarchies with ancestor and children lookups. Useful when you're building healthcare tools, analyzing genomic data, or need standardized biomedical vocabularies in your agent workflows. Hosted by Pipeworx as a standalone server or part of their broader gateway. Returns structured ontology metadata and supports pagination for large result sets.

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@pipeworx/ebi-ols

EBI Ontology Lookup Service (OLS) MCP — search and traverse ~250 biomedical ontologies (GO, EFO, MONDO, CL, ChEBI, HP, …). Keyless.

Part of Pipeworx — an MCP gateway connecting AI agents to 1476+ live data sources.

Tools

  • list_ontologies(size?, page?) — list all loaded ontologies
  • get_ontology(id) — ontology metadata (latest release, term count, …)
  • search(query, ontology?, type?, exact?, rows?) — full-text search across terms
  • get_term(ontology, iri|short_form|obo_id) — term details
  • term_ancestors(ontology, iri) — transitive parents
  • term_children(ontology, iri) — direct children

Data source

https://www.ebi.ac.uk/ols4/api/

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "ebi-ols": {
      "url": "https://gateway.pipeworx.io/ebi-ols/mcp"
    }
  }
}

What this endpoint actually serves

tools/list at https://gateway.pipeworx.io/ebi-ols/mcp returns the tools in the table above plus the shared Pipeworx meta-tools — ask_pipeworx, discover_tools, search_within, remember/recall and the rest of the gateway-wide set. So the tool count you see is larger than this table: a single-pack endpoint currently lists roughly 30 shared tools alongside the pack's own. The connection's initialize response states its exact scope, and is the authoritative answer for a given day.

This is deliberate, not multiplexing by accident. The meta-tools are what let a scoped connection answer a question this pack does not cover — via ask_pipeworx, which routes across the whole catalog — without you adding a second MCP server. There is currently no way to mount a pack endpoint without them; if the extra schemas cost you more context than the routing is worth, connect to the full gateway once rather than to several pack endpoints.

Or connect to the full Pipeworx gateway to get every pack's tools listed directly, instead of just this one's:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Both URLs reach the same gateway and the same 1476+ data sources. The only difference is which pack's tools are listed directly; ask_pipeworx reaches all of them from either one.

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English — this works on the pack endpoint above as well as on the full gateway:

ask_pipeworx({ question: "your question about Ebi Ols data" })

The gateway picks the right tool and fills the arguments automatically.

More

  • Docs and guides
  • pipeworx.io

License

MIT

No MCP client? Call it over HTTP

curl -X POST https://gateway.pipeworx.io/v1/tools/list_ontologies \
  -H 'Content-Type: application/json' \
  -d '{"size":20,"page":0}'

No account needed for the first calls. Inspect any tool: GET https://gateway.pipeworx.io/v1/tools/list_ontologies. Find one: POST https://gateway.pipeworx.io/v1/tools/search_packs with {"query":"..."}.

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TransportHTTP
UpdatedMay 14, 2026
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