Monarch Initiative

Connects Claude to the Monarch Initiative's biomedical knowledge graph, letting you search across diseases, phenotypes, genes, and variants without leaving your editor. You get five focused tools: full-text search across nodes, entity lookup by curie identifiers like MONDO:0007947, association queries between entities, phenotype-to-gene mapping for HP terms, and gene-to-disease linking for NCBIGene or HGNC identifiers. Runs through Pipeworx's gateway over streamable HTTP, so no local setup. Useful when you're prototyping healthcare tools, exploring rare disease relationships, or need to validate gene-phenotype connections during research workflows.