Summary
Connects Claude to the Open Targets Platform's disease, target, and drug knowledge graph via GraphQL. You get seven tools for querying gene profiles by Ensembl ID, disease data by EFO ID, drug info by ChEMBL ID, and cross-entity search. The association tools let you find which diseases link to a target and vice versa, plus known drugs tested against specific targets. Part of the Pipeworx gateway, which routes to 673+ data sources. Reach for this when you need programmatic access to validated therapeutic hypotheses, genetic evidence for drug targets, or clinical trial data without writing GraphQL queries yourself.
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mcp-opentargets
Open Targets MCP — disease/target/drug knowledge graph.
Part of Pipeworx — an MCP gateway connecting AI agents to 673+ live data sources.
Tools
| Tool | Description |
|---|---|
target | Target (gene) profile by Ensembl id. |
disease | Disease profile by EFO id. |
drug | Drug profile by ChEMBL id. |
search | Platform search across diseases/targets/drugs. |
target_associations | Top disease associations for a target. |
disease_associations | Top target associations for a disease. |
target_known_drugs | Drugs clinically tested against a target. |
Quick Start
Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):
{
"mcpServers": {
"opentargets": {
"url": "https://gateway.pipeworx.io/opentargets/mcp"
}
}
}
Or connect to the full Pipeworx gateway for access to all 673+ data sources:
{
"mcpServers": {
"pipeworx": {
"url": "https://gateway.pipeworx.io/mcp"
}
}
}
Using with ask_pipeworx
Instead of calling tools directly, you can ask questions in plain English:
ask_pipeworx({ question: "your question about Opentargets data" })
The gateway picks the right tool and fills the arguments automatically.
More
License
MIT
Featured
Notes, actions and memory. Without a meeting bot. First month 100% off.
Download for free →Keep your Mac awake while Claude Code and 40+ AI agents run. Sleeps when they're idle.
One time payment $9 →Give your AI agent a complete email layer—sending, inbound inboxes, and sandbox testing.
Get 4K emails/month free →Integrate web data into your AI product. One API to scrape website & brand data.
Get API Key Now →Your agent targets a perfect 10 Code Health score. Deterministic. Every commit.
Try For Free →Agent, run crypto. Access onchain data & trade routes via 1inch.
Install now →
